Table 1.
Prognostic factors | Clinical signs | Laboratory data |
Prognostic factor I (2 points for each positive factor) | Shock | BE ≤ -3 mmol/L |
Respiratory failure | Ht ≤ 30% (after hydration) | |
Mental disturbance | BUN ≥ 40 mg/dL or creatinine ≥ 2.0 mg/dL | |
Severe infection | ||
Hemorrhagic diathesis | ||
Prognostic factor II (1 points for each positive factor) | PaO2 ≤ 60 mmHg (room air) | |
FBS ≥ 200 mg/dL | ||
Total protein ≤ 60 g/L | ||
LDH ≥ 700 IU/L | ||
Ca ≤ 7.5 mg/dL | ||
Prothrombin time ≥ 15 s | ||
Platelet count ≤ 1 × 105/mm3 | ||
CT grade IV or V | ||
Prognostic factor III | SIRS score ≥ 3 (2 points) | |
Age ≥ 70 yr (1 point) |
BE: Base excess; Ht: Hematocrit; BUN: Blood urea nitrogen; FBS: Fasting blood sugar; LDH: Lactate dehydrogenase; SIRS: Systemic inflammatory response syndrome. CT grade IV or V: Presence of diffuse and uneven density in the pancreatic parenchyma or the presence of inflammatory changes extending beyond the border of the pancreas. Severity score: Sum of the points for the positive prognostic factors is defined as the severity score. Standardized criteria: Severe, presence of more than one prognostic factor I, and/or the presence of more than two prognostic factor II (severity score ≥ 2 points); Moderate, presence of one prognostic factor II (severity score = 1 point); Mild, acute pancreatitis without prognostic factor I or II (severity = 0 point).