Table 3. Primary Causes of Graft Loss after 10 Years, by Transplant Number and Donor Source (All Recipients).
Primary DD
(n=331) |
Primary LD
(n=507) |
Retransplant DD
(n=91) |
Retransplant LD
(n=40) |
|
---|---|---|---|---|
Acute rejection (AR), n (%) | 2 (.6%) | 5 (1%) | 1 (1%) | 3 (7.5%) |
Chronic rejection/CAN, n (%) | 92 (28%) | 132 (26%) | 32 (35%) | 16 (40%) |
Death with function, n (%) | 176 (53%) | 260 (51%) | 33 (36%) | 12 (30%) |
Recurrent disease, n (%) | 10 (3%) | 32 (6%) | 3 (3%) | 1 (3%) |
De novo disease, n (%) | 3 (1%) | 1 (0.2%) | 1 (1%) | -- |
Noncompliance, n (%) | 7 (2%) | 18 (4%) | 2 (2%) | 4 (10%) |
Unknown, n (%) | 22 | 30 | 10 | 3 |
CNI toxicity, (%) | 2 (1%) | -- | -- | -- |
Other, n (%)* | 17 (5%) | 29 (6%) | 9 (10%) | 1 (3%) |
Legend:
CAN = Chronic allograft nephropathy
DD = Deceased donor
LD = Living donor
CNI = calcineurin inhibitor
(= late technical, malignancy, infection, pre-renal)