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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Am J Transplant. 2008 Nov;8(11):2410–2419. doi: 10.1111/j.1600-6143.2008.02414.x

Table 3. Primary Causes of Graft Loss after 10 Years, by Transplant Number and Donor Source (All Recipients).

Primary DD
(n=331)
Primary LD
(n=507)
Retransplant DD
(n=91)
Retransplant LD
(n=40)
Acute rejection (AR), n (%) 2 (.6%) 5 (1%) 1 (1%) 3 (7.5%)
Chronic rejection/CAN, n (%) 92 (28%) 132 (26%) 32 (35%) 16 (40%)
Death with function, n (%) 176 (53%) 260 (51%) 33 (36%) 12 (30%)
Recurrent disease, n (%) 10 (3%) 32 (6%) 3 (3%) 1 (3%)
De novo disease, n (%) 3 (1%) 1 (0.2%) 1 (1%) --
Noncompliance, n (%) 7 (2%) 18 (4%) 2 (2%) 4 (10%)
Unknown, n (%) 22 30 10 3
CNI toxicity, (%) 2 (1%) -- -- --
Other, n (%)* 17 (5%) 29 (6%) 9 (10%) 1 (3%)

Legend:

CAN = Chronic allograft nephropathy

DD = Deceased donor

LD = Living donor

CNI = calcineurin inhibitor

*

(= late technical, malignancy, infection, pre-renal)