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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Am J Transplant. 2008 Nov;8(11):2410–2419. doi: 10.1111/j.1600-6143.2008.02414.x

Table 5. Primary Causes of Graft Loss after 10 Years, by Interval Posttransplant and Donor Source (Primary Transplant Recipients).

10 through 14 years 15 through 19 years 20 through 24 years
DD
(n=205)
LD
(n=267)
DD
(n=81)
LD
(n=131)
DD
(n=29)
LD
(n=65)
Acute rejection (AR), n (%) 2 (1%) 4 (2%) -- 1 (1%) -- --
Chronic rejection (CAN), n (%) 57 (28%) 78 (29%) 19 (23%) 32 (24%) 12 (43%) 11 (17%)
Death with function, n (%) 112 (55%) 130 (49%) 43 (53%) 68 (52%) 14 (50%) 38 (58%)
Recurrent disease, n (%) 6 (3%) 21 (8%) 3 (4%) 8 (6%) -- 3 (5%)
De novo disease, n (%) 1 (.5%) -- 1 (1%) -- 1 (4%) --
Noncompliance, n (%) 4 (2%) 9 (3%) 1 (1%) 3 (2%) -- 3 (5%)
CNI-toxicity, n (%) 1 (.5%) -- 1 (1%) -- -- --
Unknown, n (%) 3 (1%) 6 (2%) 2 (2%) 4 (3%) -- 2 (3%)
Other, n (%) 19 (9%) 19 (7%) 11 (14%) 17 (13%) 1 (4%) 8 (12%)

Legend:

CAN = Chronic allograft nephropathy

DD = Deceased donor

LD = Living donor

CNI = Calcineurin inhibitor