TABLE 5.

Mean (± S.E.M.) potency (ED₅₀, mg/kg) for test drugs to decrease rates of responding by 50% in male and female cynomolgus monkeys trained to discriminate 1.0 or 2.0 g/kg ethanol

The number of monkeys showing dose-dependent decreases in response rate during vehicle tests to the number of monkeys tested is shown in parentheses.

Test Drug	1.0 g/kg Ethanol Training		2.0 g/kg Ethanol Training
	Females	Males	Females	Males
Ethanol	(0/4)	843 (1/6)	(0/4)	(0/3)
Pentobarbital	8.52 (1/4)	(0/6)	(0/4)	NC a (1/3)
Midazolam	4.71 (1/4)	4.73 ± 1.75 (3/6)	5.98 ± 2.71 (2/4)	6.89 (1/2)

^a NC, not calculable because the maximum percentage of the baseline response rate is <50%.