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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Genet Epidemiol. 2009 Sep;33(6):479–487. doi: 10.1002/gepi.20400

Figure 3.

Figure 3

Pr[G1 > c] as a function of recombination rate (r), mutation rate (µ), disease frequency (pD), penetrance of the low-risk homozygous genotype (pL), penetrance of the high-risk homozygous genotype (pH), and relative risk (pH/pL). For each of these variables, the 100,000 simulated studies were binned into 100 groups each consisting of 1000 studies. The probability evaluated from the studies in a bin is plotted at the mean of the 1000 values placed in the bin. The plots are based on demographic Model 2 with the recessive disease model.