TABLE VII.

Nicotine (N), cotinine(CO), and caffeine (CA) levels in ng/ml in plasma (P), saliva (S), and urine (U) of twelve healthy adult volunteers at baseline before the administration of (S)-5-[¹²³I]iodo-3-(2-azetidinylmethoxy)pyridine (5-[¹²³I]IA) unless noted otherwise

Subject number	P N	P CO	P CA	S N	S CO	S CA	U N	U CO	U CA
1 eight days prior to injection of 5IA	2.80	<10.0	35.5	4.07	<10.0	23.7	<1.0	<10.0	40.2
1 day of injection of 5IA	55.3	<10.0	187	0	0	107	<1.0	<10.0	75.7
2	1.63	19.4	22.4	0	0	<20.0	0	0	<20.0
3	14.1	39.9	576	224	213	685	1.72	42.6	804
4	<1.0	<10.0	268	<1.0	18.5	559	0	<10.0	370
5	0	<10.0	119	0	<10.0	91.8	1.32	69.6	151
6	0	<10.0	354	0	<10.0	299	3.88	85.9	475
7	2.92	103	216	2.86	140	207	391	1160	207
8	<1.0	<10.0	0	<1.0	<10.0	0	<1.0	<10.0	0
9	<1.0	71.4	<20.0	<1.0	69.5	0	172	532	0
10	0	<10.0	61.9	<1.0	<10.0	157	8.22	<10.0	140
11	<1.0	0	<20.0	<1.0	<10.0	<20.0	0	<10.0	25.7
12	3.20	153.2	105.4	37	163.1	<20.0	172.2	1145.8	176.9