Figure 2.

Distribution of DCX+ cells in the temporal lobe cortical areas surrounding the amygdala (A–K), in the insular (Ins) and secondary somatosensory (S2) cortex (L), and in the ventral prefrontal cortex including the medial and lateral orbital gyri (MOG, LOG) (M–O) in a 22-year-old rhesus monkey. Framed areas in lower magnification panels are enlarged sequentially as indicated. DCX+ cells in the amygdala (Amyg) are located near the white matter deep to the entorhinal cortex (Ent) as a cellular band, which continues into the adjoining Ent and further dorsally into the inferior temporal gyrus (ITG) around the border of layers I and II (A–C). Labeled cells are mostly small and bipolar, often arrange as clusters and chains with cells seemingly migrate outside-in intracortically (C,F). However, in the ITG a large number of cells are associated with tangentially arranged migratory chains that can extend very long (D,G–K). Some of these chains appear to extend from layer I and then enter the cortical plate, with cells dispatching or being dispersed around the end of the chains (D,J,K, green arrows). Note that labeled cells are also fairly common in the MOG and LOG (M,N), but fewer in the Ins cortex and S2 (L). A few relatively large cells with reduced DCX reactivity are present in layers II/III (indicated with black arrows in K,N,O). rf, rhinal fissure; LF, lateral fissure. Arab numbers indicate cortical layers. Scale bar = 3 mm in (A) applying to (E,F), equivalent to 1 mm for (B,C), 500 μm for (D), 100 μm for (G,H,L–N) and 50 μm for (E,F,I–K,O).