Table 1.
Comparison of hippocampal with cortical DCX+ cells.
| Features or observations | SGZ | Layers II/III |
|---|---|---|
| Transient expression of immature neuronal markers1 | Yes | Yes |
| Partial co-expression of mature neuronal markers2 | Yes | Yes |
| Heterogeneous developing neuronal | Yes | Yes morphology |
| Response to antidepressants | Yes | Likely |
| Time of cell presence during postnatal life | To mid-age | Life long |
| Migration | Across the GCL | Inwardly |
| Definitive or putative destiny | Granule cells | Interneurons |
| BrdU incorporation | Yes | Inconsistent |
| Retrovirus incorporation | Yes | No report |
1DCX, PSA-NCAM, neuron-specific β-tubulin-III (TuJ1) and Hu.
2NeuN and some terminal phenotype markers of interneurons.