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Schematic of purine metabolism in S. cerevisiae. Ado, adenosine; AICAR, 5′-phosphoribosyl-5-amino-4-imidazole carboxamide; Ino, inosine; IMP, inosine 5′-monophosphate; and PRPP, 5-phosphoribosyl-1-pyrophosphate. Gene names are italicized. For simplicity, only the enzymatic steps cited in the text are shown in the figure. Putative adenosine deaminase activity is indicated by a question mark.
