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. 2009 Oct;183(2):563–579. doi: 10.1534/genetics.109.105585

TABLE 3.

Molecular lesions associated with sax alleles

Allele Nucleotide change Codon change saxn/Df(sax) phenotype
Newly described alleles
    sax3 CAG→TAG Gln 121 stop Lethal*
    sax4 CAA→TAA Gln 114 stop Lethal
    sax5 GCC→GAC Ala 289 Asp Lethal
    sax6 CGC→CAG Arg 541 His Lethal
    saxPb P[lacW] insertion After aa 34 of Sax-PA Viable
Previously described alleles
    sax1a ACC→ATC Thr 434 Ile Viable
    sax2a GGA→GAA Gly 412 Glu Viable

saxn, new sax allele; *sax3/Df(sax) exhibits weak (0.6–2%) viability.

b

Isolated by Török et al. 1993; previously described in Nellen et al. 1994 as a P-element insertion after the first 36 amino acid residues of the SAX protein.