Table 1.
Study Cohorts
Cohort | BA7072 Concentration In Vitro (µg/mL) |
Nucleated Cells Infused |
Product Configuration |
Disease Type (No. Patients) |
Total No. Patients |
||||
---|---|---|---|---|---|---|---|---|---|
Breast | Ovarian | Colorectal | |||||||
1 | 10 | 1 × 109 | Fresh and Cryopreserveda |
1 | 3 | 1 | 5 | ||
2 | 40 | 1 × 109 | Fresh and Cryopreserveda |
2 | 1 | 2 | 5 | ||
3 | 40 | 1 × 109 | Cryopreserved Onlyb |
8 | 0 | 0 | 8 |
One infusion of fresh lapuleucel-T followed by 2 infusions of cryopreserved lapuleucel-T.
Three infusions of cryopreserved lapuleucel-T.