FIG. 5.

Hippocampal CA3 cell density. Representative Nissl-stained coronal sections from the treatment groups. (a) Image from a normal, uninjured animal, showing many healthy neurons with pale, plump nuclei and prominent nucleoli. (b) Image from a vehicle-treated animal, displaying striking neuronal loss. (c) Image from a free tPA-treated animal, showing intermediate neuronal loss. (d) Image from an RBC/tPA-treated animal, showing only modest neuronal loss (original magnification 20x×; bar = 50 μm).