Table 1.
Frequency of crossover inhibition and average rectification in various broad cell classes
| General cell class | fraction with crossover | R ( degree of Rectification) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Excitation | Inhibition | Voltage | |||||||||
| raw # | By type | mean | std | p | mean | std | p | mean | std | p | |
| OFF BC | 44/48 (48/48) | 5/6 (6/6) | -0.26 | 0.25 | 5.4E-08 | 0.37 | 0.35 | 4.6E-07 | -0.12 | 0.48 | 0.037 |
| ON BC | 26/49 (38/49) | 2/5 (3/5) | -0.09 | 0.2 | 2.5E-02 | 0.17 | 0.51 | 8.4E-02 | -0.15 | 0.43 | 0.04 |
| OFF AC | 38/86 (62/86) | 6/13 (11/13) | -0.61 | 0.32 | 7.7E-07 | 0.21 | 0.54 | 3.7E-02 | 0.1 | 0.58 | 0.16 |
| ON ACa | 90/119 (106/119) | 12/17 (16/17) | -0.27 | 0.29 | 1.1E-08 | 0.28 | 0.4 | 1.1E-05 | -0.1 | 0.4 | 0.014 |
| OFF GC | 44/67 (67/67) | 4/5 (5/5) | -0.46 | 0.34 | 1.3E-03 | 0.23 | 0.42 | 6.3E-02 | N/A | N/A | N/A |
| ON GC | 10/67 (54/67) | 1/5 (4/5) | -0.2 | 0.21 | 1.3E-01 | 0.1 | 0.39 | 1.0E + 00 | N/A | N/A | N/A |
Frequency of crossover inhibition across all cells measured, pooled from previous work and more recent experiments: numbers indicate proportion where crossover inhibition is dominant over other types of inhibition, numbers in parentheses indicate proportion where crossover is present, but not necessarily dominant. Cells were also categorized into various sub-types and frequency of crossover across sub-types is also shown. Cell type categorization was based upon morphological classification using depth, width and diffuseness of IPL stratification, as described in (Hsueh et al. 2008; MacNeil et al. 2004, 1999; Molnar and Werblin 2007; Rockhill et al. 2002; Roska et al. 2006). Rectification (not previously reported) was analyzed across all cells of a given class that received crossover inhibition. Mean, standard deviation and significance (analyzed using a Wilcoxan signed-rank test) were derived for each subclass. aAII amacrine cells were explicitly eliminated from this pool, as poor space clamp through gap junctions made it very difficult to separate excitation from inhibition(Hsueh et al. 2008).