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. 2008 Mar 31;56(2):127–134. doi: 10.1007/s00005-008-0009-2

Table. 1.

Distribution of MNA and NA added to the culture of LPS-stimulated macrophages

Exogenous compounds (µM)a Final concentrationb The ratio of medium to cytosol concentration
medium cytosol
MNA (0.0) <0.1 <0.5 ND
MNA (10.000) 7991±461 223±32 35.8
NA (0.0) 9±1 47±3 ND
NA (4.000) 3598±87 420±26 8.57

aMNA or NA was added to the culture of LPS-stimulated Mϕ at the concentrations indicated in brackets. bAfter 24 h, supernatant and Mϕ were collected separately and the concentrations of extracellular (medium) and intracellular (cytosol) MNA and NA were measured as described in Materials and Methods. ND — not done.