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. Author manuscript; available in PMC: 2009 Oct 25.
Published in final edited form as: Biometals. 2009 Feb 17;22(4):633–648. doi: 10.1007/s10534-009-9218-3

Table 2.

Growth promotion activity of desferridanoxamine (Dan) relative to standards ferricrocin (F) and mycobactin J (M). 5 μL Dan (2.0 mM), 1 μL F (1 mg/mL), and 5 μL M (400 μg/mL) were applied to 6 mm paper discs on iron deficient media as described (Schuman and Möllmann 2001). Growth zones read after incubation at 37°C for 24 h (mycobacteria 72 h).

Test Organism/Compound Zone of Growth Promotion (mm)
Dan
2.0 mM		 F
1 mg/mL		 M
400 μg/mL
B. subtilis ATCC 6633 30 40 nt
S. aureus SG511 16 30 nt
M. phlei M77 0 nt 15
M. smegmatis mc2155 17 nt 22
M. smegmatis mc2155-M24 18 nt 20
M. smegmatis mc2155-B1 0 nt 14.5
M. smegmatis mc2155-M24-B3(35) 0 nt 17
M. smegmatis mc2155-M24-U3(47) 0 nt 19
S. typhimurium enb-7 16 23 nt
E. coli AB2847 0 28 nt
E. coli BR158 0 0 nt
E. coli H1876 0 29.5 nt
E. coli HK9/7 0 0 nt
E. coli MS172 0 30 nt
E. coli 41/2 0 10 nt
P. aeruginosa ATCC 27853 33 40 nt
P. aeruginosa PAO 6609 20 28 nt
P. aeruginosa K648 28 40 nt
P. aeruginosa K199 20 36 nt