Table 3.

Growth inhibition activity of desferrisalmycin B (Sal B) and epi-desferrisalmycin B (epi-Sal B) relative to standards desferridanoxamine (Dan), salmycin A (Sal A), ciprofloxacin (Cip), albomycin (Alb), and kanamycin (Kan). 50μL of a 100 mg/L solution of each compound was filled in 9 mm wells in agar media (Standard I Nutrient Agar, Serva). Inhibition zones read after incubation at 37°C for 24 h (Möllmann et al. 2004).

Test Organism/Compound	Zone of Growth Inhibition (mm)
	Dan 0.16 mM	epi-Sal B 0.1 mM	Sal B 0.1 mM	Sal A 0.1 mM	Alb 0.1 mM	Cip 0.3 mM	Kan 0.21 mM
B. subtilis ATCC 6633	0	12r	12r	31	22r	28	26
S. aureus SG 511 (Fig. 5A)	0	26	30	35	33r	18	22.5
S. aureus 134/93 (Fig. 5B)	0	19	27	38	26r	0	0
S. aureus 994/93 (Fig. 5C)	0	24r	24	33.5	34r	0	0
S. aureus EfS4 (Fig. 5D)	0	22r	22.5sr	31.5sr	0	0	19.5sr
K. pneumoniae ATCC 10031	0	0	0	25	30	30	22
E. coli DC0	0	0	0	0	25	17	19
E. coli DC2	0	0	0	0	36	20.5	18.5
P. aeruginosa ATCC 27853	0	0	0	0	0	19	0

r = confluent distribution of resistant colonies within the inhibition zone

sr = single resistant colonies within the inhibitio n zone