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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Exp Neurol. 2009 Mar 28;217(2):361–370. doi: 10.1016/j.expneurol.2009.03.021

Table 5.

Mean optical density of MBP staining following cerebral HI

P9 P22
Sham 0.0472±0.007 (n=11) 0.170±0.021 (n=5)
Control 0.009±0.004* (n=11) 0.080±0.050* (n=5)
IGF-PT0h 0.033±0.014*# (n=11) 0.124±0.015*# (n=6)
IGF-PT1h 0.028±0.010*# (n=11) 0.130±0.023*# (n=6)

Mean optical density of MBP staining was determined as described in Methods. Cerebral HI decreased the MBP staining in both the P9 and P22 rat brain, while IGF-1 treatment at 0 or 1 h after HI partially reversed the HI-induced hypomyelination.

*

P<0.05 as compared to the sham group.

#

P<0.05 as compared to the HI control group.