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. Author manuscript; available in PMC: 2009 Oct 25.
Published in final edited form as: Am Heart J. 2007 Jan;153(1):54–58. doi: 10.1016/j.ahj.2006.10.019

Table 1.

Baseline characteristics of the pravastatin and usual care subgroups, according to ACE insertion/deletion genotype.

ACE Genotype
II ID DD
Characteristic Pravastatin Usual care Pravastatin Usual care Pravastatin Usual care
Sample size 951 (20.1) 922 (19.5) 2376 (50.1) 2336 (49.4) 1414 (29.8) 1468 (31.1)
Age 65.95 (7.5) 66.13 (7.8) 66.64 (7.7) 66.17 (7.4) 66.32 (7.8) 66.34 (7.6)
Race
 White 551 (57.9) 567 (61.5) 1358 (57.2) 1367 (58.5) 778 (55.1) 806 (54.9)
 Black 304 (32.0) 274 (29.7) 897 (37.8) 824 (35.3) 572 (40.4) 587 (40.0)
 Other 96 (10.1) 81 (8.8) 121 (5.0) 145 (6.2) 64 (4.5) 75 (5.1)
Gender (Male) 481 (50.6) 471 (51.1) 1218 (51.3) 1185 (50.7) 735 (52.0) 747 (50.9)
Lipid Meds in last year 14 (1.5) 19 (2.1) 38 (1.6) 33 (1.4) 27 (1.9) 20 (1.4)
SBP, mm Hg 145 (13.9) 146 (14.2) 145 (14.1) 145 (13.9) 145 (13.7) 145 (14.1)
DBP, mm Hg 84 (9.7) 84 (9.9) 84 (10.0) 84 (9.7) 84 (9.6) 84 (10.0)
Smoker 211 (22.2) 245 (26.6) 548 (23.1) 525 (22.5) 353 (25.0) 339 (23.1)
History of diabetes 359 (37.8) 286 (31.0) 843 (35.5) 834 (35.7) 477 (33.7) 501 (34.1)
History of MI or Stroke 164 (17.3) 145 (15.7) 397 (16.7) 408 (17.5) 248 (17.5) 268 (18.3)
History of CHD 131 (13.8) 146 (15.8) 333 (14.0) 344 (14.7) 178 (12.6) 227 (15.5)
BMI 30.1 (6.0) 29.7 (6.2) 29.8 (5.9) 29.9 (6.1) 29.8 (5.9) 30.2 (6.2)
Total cholesterol 224.7 (26.2) 223.1 (26.3) 223.2 (27.3) 223.5 (26.3) 223.5 (26.9) 223.9 (26.6)
HDL cholesterol 47.0 (13.6) 46.9 (13.5) 47.6 (13.4) 47.2 (13.2) 47.9 (13.3) 47.7 (13.9)
LDL cholesterol 145.5 (20.5) 144.9 (20.9) 145.2 (21.9) 145.3 (21.4) 145.8 (21.1) 145.5 (21.3)
Antihypertensive treatment group
Doxazosin 180 (18.9) 194 (21.0) 497 (20.9) 508 (21.8) 316 (22.3) 309 (21.1)
Chlorthalidone 367 (38.9) 348 (37.7) 838 (35.3) 850 (36.4) 513 (36.3) 516 (35.2)
Amlodipine 196 (20.6) 197 (21.4) 536 (22.6) 501 (21.5) 292 (20.7) 315 (21.5)
Lisinopril 208 (21.9) 183 (19.9) 505 (21.3) 477 (20.4) 293 (20.7 328 (22.3)