Table 1.
ACE Genotype |
||||||
---|---|---|---|---|---|---|
II | ID | DD | ||||
Characteristic | Pravastatin | Usual care | Pravastatin | Usual care | Pravastatin | Usual care |
Sample size | 951 (20.1) | 922 (19.5) | 2376 (50.1) | 2336 (49.4) | 1414 (29.8) | 1468 (31.1) |
Age | 65.95 (7.5) | 66.13 (7.8) | 66.64 (7.7) | 66.17 (7.4) | 66.32 (7.8) | 66.34 (7.6) |
Race | ||||||
White | 551 (57.9) | 567 (61.5) | 1358 (57.2) | 1367 (58.5) | 778 (55.1) | 806 (54.9) |
Black | 304 (32.0) | 274 (29.7) | 897 (37.8) | 824 (35.3) | 572 (40.4) | 587 (40.0) |
Other | 96 (10.1) | 81 (8.8) | 121 (5.0) | 145 (6.2) | 64 (4.5) | 75 (5.1) |
Gender (Male) | 481 (50.6) | 471 (51.1) | 1218 (51.3) | 1185 (50.7) | 735 (52.0) | 747 (50.9) |
Lipid Meds in last year | 14 (1.5) | 19 (2.1) | 38 (1.6) | 33 (1.4) | 27 (1.9) | 20 (1.4) |
SBP, mm Hg | 145 (13.9) | 146 (14.2) | 145 (14.1) | 145 (13.9) | 145 (13.7) | 145 (14.1) |
DBP, mm Hg | 84 (9.7) | 84 (9.9) | 84 (10.0) | 84 (9.7) | 84 (9.6) | 84 (10.0) |
Smoker | 211 (22.2) | 245 (26.6) | 548 (23.1) | 525 (22.5) | 353 (25.0) | 339 (23.1) |
History of diabetes | 359 (37.8) | 286 (31.0) | 843 (35.5) | 834 (35.7) | 477 (33.7) | 501 (34.1) |
History of MI or Stroke | 164 (17.3) | 145 (15.7) | 397 (16.7) | 408 (17.5) | 248 (17.5) | 268 (18.3) |
History of CHD | 131 (13.8) | 146 (15.8) | 333 (14.0) | 344 (14.7) | 178 (12.6) | 227 (15.5) |
BMI | 30.1 (6.0) | 29.7 (6.2) | 29.8 (5.9) | 29.9 (6.1) | 29.8 (5.9) | 30.2 (6.2) |
Total cholesterol | 224.7 (26.2) | 223.1 (26.3) | 223.2 (27.3) | 223.5 (26.3) | 223.5 (26.9) | 223.9 (26.6) |
HDL cholesterol | 47.0 (13.6) | 46.9 (13.5) | 47.6 (13.4) | 47.2 (13.2) | 47.9 (13.3) | 47.7 (13.9) |
LDL cholesterol | 145.5 (20.5) | 144.9 (20.9) | 145.2 (21.9) | 145.3 (21.4) | 145.8 (21.1) | 145.5 (21.3) |
Antihypertensive treatment group | ||||||
Doxazosin | 180 (18.9) | 194 (21.0) | 497 (20.9) | 508 (21.8) | 316 (22.3) | 309 (21.1) |
Chlorthalidone | 367 (38.9) | 348 (37.7) | 838 (35.3) | 850 (36.4) | 513 (36.3) | 516 (35.2) |
Amlodipine | 196 (20.6) | 197 (21.4) | 536 (22.6) | 501 (21.5) | 292 (20.7) | 315 (21.5) |
Lisinopril | 208 (21.9) | 183 (19.9) | 505 (21.3) | 477 (20.4) | 293 (20.7 | 328 (22.3) |