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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Magn Reson Med. 2009 Aug;62(2):384–393. doi: 10.1002/mrm.21980

Figure 1.

Figure 1

A) Effect of duration and power of RF irradiation on the DSR signal intensity for gray matter (T2 = 70ms; T1 = 1100ms; offset = 100Hz; Eqns. 3-8). Short duration and high power provides rapid saturation, but longer pulses with much less power achieve saturation in approximately 200 ms. B) saturation spectra with (dotted line) and without (solid line) MT effect as a function of offset frequency for 4 saturation pulse amplitudes at tsat = 250ms (simulation using full Bloch Equations). For this pulse duration, at higher power and greater offset frequencies, the MT effect starts to contribute substantially to signal intensity. C) DSR change for a 15% decrease in T2, (Eqs. 3-8; B1 = 0.8μT and tsat = 250 ms). The offset corresponding to the greatest DSR difference is in the range of 120 – 140 Hz.