Figure 1.
Infarct repair in MRL/MpJ and C57BL/6 mouse hearts. Midlevel cross-sections of C57BL/6 and MRL/MpJ mouse hearts from sham operated mice and 1, 4, 14 and 90 days after myocardial infarction stained by hematoxylin and eosin (A) and sirius red and fast green (B) show a progression from necrosis at day 1 (C) to granulation tissue at day 4 (D) to scar and compensatory septal hypertrophy (days 14 and 90). Each feature is comparable between strains. (Bars = 1 mm and 50 μm) (E) Infarct size as a percent of the left ventricular circumference is similar in both strains at all times.
