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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Eur J Neurosci. 2009 Oct 8;30(8):1576–1584. doi: 10.1111/j.1460-9568.2009.06933.x

Figure 3.

Figure 3

Stress exposure during increased NAc 5-HT1B receptor expression subsequently enhances the acute locomotor response to amphetamine. (A) The mean (± SEM) number of crossovers made during the first 60 min of each treatment of the multiple-dose acute locomotor response test (habituation (Hab), followed 60 min later by saline treatment (Sal), followed 60 min later by 0.5 and 2 mg/kg amphetamine, injections spaced 90 min apart). Grey circles represent the GFP group and black squares represent the 5-HT1B group. *, differs from the GFP group (p < 0.05, Two-way repeated measures ANOVA, Bonferroni’s test). (B) Illustration of experimental design. (c) The mean (± SEM) number of crossovers made over time (6-min intervals) during the acute locomotor response test. N = 9–11/group.