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. Author manuscript; available in PMC: 2009 Oct 26.
Published in final edited form as: Prog Nucleic Acid Res Mol Biol. 2008;82:147–197. doi: 10.1016/S0079-6603(08)00005-6

Table I. Summary of Nitroxide Labeling Schemes that Use Solid-Phase Chemical Synthesis.

Nitroxide attachment site Examples of chemical structure References
1 Phosphate graphic file with name nihms140965t1.jpg [22]
2 Sugar: 2′-position graphic file with name nihms140965t2.jpg [23, 24]
3 Base: 4-position of uridine graphic file with name nihms140965t3.jpg [31, 46]
4 Base: acetylene linkage graphic file with name nihms140965t4.jpg [27, 30, 32, 34]
5 Base: 5-position of pyrimidines with variable tethers (2-11 atom) graphic file with name nihms140965t5.jpg [11]
6 Fused base graphic file with name nihms140965t6.jpg [28, 33]