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. 2009 Nov 5;4(11):e7638. doi: 10.1371/journal.pone.0007638

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Brettschneider et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Figure shows biomarkers that help to evaluate the risk of multiple sclerosis in patients with clinically isolated syndrome (CIS). MRI = lesion load in T2-weighted magnetic resonance imaging (lesions >3 mm²), OCB = oligoclonal bands in cerebrospinal fluid (CSF), MRZR = MRZ reaction, antibodies to measles, rubella and varicella zoster virus in CSF with two or more AI (antibody indices) ≥1.5. RRMS = relapsing-remitting multiple sclerosis.