Table 1. Demographic data, CSF and MRI findings in patients with clinically isolated syndrome (CIS).
| CIS all | CIS-CIS | CIS-RRMS | S* | ||
| n (female/male) | 89 (56/33) | 40 (22/18) | 49 (34/15) | NS | |
| Age [years] | Median (Range) | 38.5 (13.1–70.9) | 38.4 (16.8–70.9) | 39.4 (13.1–63.6) | NS |
| EDSS | Median (Range) | 2 (0–5) | 2 (0–5) | 3 (0–5) | NS |
| Measles AI≥1.5 | n (%) | 37 (42) | 11 (33) | 26 (59) | NS |
| Rubella AI ≥1.5 | n (%) | 32 (36) | 9 (24) | 23 (49) | p = 0.03 |
| Zoster AI ≥1.5 | n (%) | 32 (36) | 12 (32) | 20 (42) | NS |
| MRZR | n (%) | 33 (37) | 10 (25) | 23 (47) | p = 0.04 |
| MRZS | n (%) | 19 (21) | 4 (10) | 15 (31) | p = 0.018 |
| OCB | n (%) | 74 (83) | 27 (68) | 47 (96) | p = 0.001 |
| MRI | n (%) | 59 (66) | 21 (53) | 38 (78) | p = 0.02 |
| Barkhof criteria | n (%) | 25 (28) | 8 (20) | 17 (35) | p = 0.125 |
CIS all = all patients with CIS, CIS-CIS = patients with CIS that remained CIS over follow-up, CIS-RRMS = CIS patients with conversion to MS over follow-up, EDSS = Kurtzke Expanded Disability Status Scale, AI = antibody index, MRZR = AI for measles, rubella, zoster, two or more AI ≥1.5, MRZS = MRZ score >10, OCB = oligoclonal bands in cerebrospinal fluid, MRI = two or more lesions in T2-weighted magnetic resonance imaging of the brain. NS = not significant, S = statistical significance. * CIS-CIS vs. CIS-RRMS