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. Author manuscript; available in PMC: 2009 Oct 26.
Published in final edited form as: Int J Cancer. 2008 Mar 1;122(5):1068–1076. doi: 10.1002/ijc.23228

Figure 1.

Figure 1

Vitamin C levels in plasma (a) and gastric tissue (b). White bars are 16 WPI; Black bars are 32 WPI. Compared to gulo−/− mice supplemented with high vitamin C (H), gulo−/− mice supplemented with low vitamin C (L) had significantly lower plasma and gastric tissue vitamin C levels (**, p < 0.01; ***, p < 0.001). Vitamin C levels in plasma and gastric tissue in gulo−/− mice supplemented with high vitamin C were comparable to those in C57BL/6 (wt) mice. H. pylori (Hp) infection had no significant effect on plasma vitamin C levels or gastric vitamin C levels in gulo−/− mice supplemented with low vitamin C or in wt mice. However, gastric tissue vitamin C levels were reduced at 16 WPI but increased at 32 WPI by H. pylori infection in gulo−/− mice supplemented with high vitamin C (*, p < 0.05).