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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: J Cell Biochem. 2009 Jul 1;107(4):600–608. doi: 10.1002/jcb.22185

Figure 1.

Figure 1

Zinc-dependent histone deacetylase inhibitors can induce transformed cell growth arrest and death by different pathways. HDAC6, histone deacetylase 6; HIF-1α, hypoxia induced factor-1α; HSP90, heat shock protein 90; PP1, protein phosphatase 1; ROS, reactive oxygen species; TBP2, thioredoxin binding protein 2; Trx, thioredoxin; VEGF, vascular endothelial growth factor.