Skip to main content
. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2009 Jun 10;50(10):4887–4897. doi: 10.1167/iovs.09-3565

Figure 4.

Figure 4

The model predicted and observed concentrations of diclofenac sodium in vitreous and RC after intravitreal injection of 0.3 mg solution. (A) Two-compartment model. (B) Two-compartment model with a distribution compartment to RC. (C) Two-compartment model with parallel elimination from the vitreous and RC. The model in (A) was selected as the best-fit model. K12, rate constant for transfer of drug from the vitreous to RC; K20, rate constant for elimination of drug from the RC compartment.