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. Author manuscript; available in PMC: 2010 Sep 2.
Published in final edited form as: J Am Chem Soc. 2009 Sep 2;131(34):12068–12069. doi: 10.1021/ja904930p

Figure 1.

Figure 1

Models of: (a) cation and (b) basic amino acid sidechain associated with major groove edge of G, (c) tethered -NH3+ in 7-(aminomethyl)-7-deazaguanine (1), (d) 7-(hydroxymethyl)-7-deazaguanine (2) and (e) 7-deazaguanine (c7G) lacking cation binding site.