Skip to main content
. 2009 Nov;11(11):1216–1225. doi: 10.1593/neo.09960

Figure 4.

Figure 4

Real-time PCR validation of the androgen-regulated genes that demonstrated response to treatment with HE3235 on oligo array analysis. We confirmed AR down-regulation concomitantly with AR activation as demonstrated by differential changes in AR-regulated genes. The addition of AED seems to attenuate the effect of HE3235 on these genes. ODC1 indicates ornithine decarboxylase 1; GPR64, G protein-coupled receptor 64; ARG2, anterior gradient homolog 2 (Xenopus laevis); SAA2, serum amyloid A2; RUNX1, runt-related transcription factor 1; hK2, human glandular kallikrein; AK5, adenylate kinase 5. Numbers in parentheses show fold change in oligo array analysis. Significant differences were detected in number of mRNA in LuCaP35V treated with HE3235 versus control tumors. *P < .05.