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. 2009 Oct;128(2):206–217. doi: 10.1111/j.1365-2567.2009.03101.x

Figure 1.

Figure 1

Diagram of the recombinase activating gene 1 (RAG1) and cbl zinc-binding domains. (a) Zinc-binding residues of the RAG1 really interesting new gene (RING) domain are shown, including the co-ordination of the third zinc ion by the non-canonical binding residues C266, H270 and H295. The first zinc site is co-ordinated by residues C290, C293, C310 and C313. The second zinc site is co-ordinated by residues C305, H307, C325 and C328. (b) The cbl diagram represents a classic RING domain with the first zinc co-ordinated by C381, C384, C401 and C404. The second zinc is co-ordinated by residues C395, H398, C416 and C419.