Figure 2.

In silico alignment of really interesting new gene (RING) structures. Backbone traces of the recombinase activating gene 1 (RAG1) RING structure with the cbl RING structure determined as a part of the cbl–UbcH7 complex are shown.24,26 Red, UbcH7; green, cbl; yellow, RAG1; magenta spheres, cbl zinc ions; grey spheres, RAG1 zinc ions. Protein Data Bank (PDB) ID for the cbl–ubcH7 co-structure is 1fbv, PDB ID for RAG1 RING is 1rmd.