Effect of GDNF on dopamine and principal metabolites in the putamen. Open columns, control animals that received a PBS infusion; hatched columns, low-dose putamen group; gray columns, substantia nigra group; solid columns, high-dose putamen group. Statistical indicators are as follows: *p < 0.05, **p < 0.01, two-way ANOVA, followed by one-way ANOVA post-hoc tests, and Newman–Keuls post-hoc comparisons with PBS group.