Table 1.
Infection status and bacterial load of X. cheopis fleas. Data are combined from fleas collected during two separate experiments. All strains were CO92 (Lcr-)
Fleas infected with | Day p.i. | Fleas Collected (n) | Infected Fleas (%) | Median (range) CFU/Flea |
---|---|---|---|---|
Y. pestis CO92 Pgm+ | 0 | 10 | 100 | 1.5 × 104 (1.2 × 102-1.6 × 105) |
3 | 40 | 97.5 | 2.9 × 103 (0.0-4.9 × 104) | |
7 | 22 | 100 | 4.7 × 103 (2.5 × 101-4.1 × 104) | |
14 | 12 | 83.3 | 9.1 × 103 (0.0-3.9 × 104) | |
21 | - | - | - | |
Y. pestis CO92 Pgm- | 0 | 5 | 100 | 1.8 × 104 (7.9 × 103-8.4 × 104) |
3 | 20 | 85 | 1.1 × 102 (0.0-3.2 × 104) | |
7 | 11 | 100 | 3.4 × 103 (6.3 × 102-4.9 × 104) | |
14 | - | - | - | |
21 | - | - | - | |
Y. pestis CO92_ΔYPO499-516 Pgm+ | 0 | 10 | 100 | 3.4 × 103 (2.6 × 102-1.8 × 105) |
3 | 40 | 100 | 1.0 × 103 (1.0-1.8 × 106) | |
7 | 31 | 96.8 | 8.1 × 103 (0.0-8.0 × 104) | |
14 | 5 | 100 | 1.7 × 103 (1.3 × 103-1.2 × 104) | |
21 | - | - | - | |
Y. pestis CO92_ΔYPO499-516 Pgm- | 0 | 10 | 100 | 2.7 × 103 (1.7 × 102-1.8 × 104) |
3 | 40 | 95 | 5.7 × 101 (0.0-1.8 × 104) | |
7 | 20 | 100 | 1.2 × 103 (2.1 × 101-1.5 × 105) | |
14 | 20 | 100 | 2.4 × 102 (1.0 × 101-2.2 × 104) | |
21 | 10 | 100 | 9.7 × 102 (2.3 × 102-5.9 × 103) | |
Y. pestis CO92_Δymt Pgm+ | 0 | 10 | 100 | 1.4 × 103 (1.0 × 102-9.2 × 103) |
3 | 26 | 61.5 | 1.5 × 101 (0.0-2.6 × 104) | |
7 | 20 | 75 | 4.5 × 102 (0.0-7.2 × 104) | |
14 | 4 | 0 | 0.0 (0.0-0.0) | |
21 | - | - | - | |
Y. pestis CO92_Δymt Pgm- | 0 | 10 | 100 | 3.7 × 103 (6.5 × 102-1.8 × 105) |
3 | 40 | 30 | 0.0 (0.0-8.6 × 104) | |
7 | 40 | 15 | 0.0 (0.0-5.6 × 101) | |
14 | 40 | 2.5 | 0.0 (0.0-3.1 × 103) | |
21 | 20 | 5 | 0.0 (0.0-1.4 × 102) | |
No | 0 | 5 | 0 | 0.0 (0.0-0.0) |
bacteria | 3 | 40 | 0 | 0.0 (0.0-0.0) |
7 | 33 | 0 | 0.0 (0.0-0.0) | |
14 | 40 | 0 | 0.0 (0.0-0.0) | |
21 | 20 | 0 | 0.0 (0.0-0.0) |