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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Immunobiology. 2009 Feb 26;215(1):70–80. doi: 10.1016/j.imbio.2009.01.015

Figure 10.

Figure 10

Inhibition of iNOS or IDO fails to negate GM-CSF-triggered suppression (panel A) and does not surpass IL-6-mediated release (panel B). In Panel A, PerC cell presentation of Mls that is further suppressed by 10 ng/ml of GM-CSF at high Mφ:T cell ratios was not recovered by blocking iNOS (1-MA), IDO (1-MT), or COX (Indo). In Panel B, addition of 50 ng/ml of IL-6 afforded the greatest recovery of the Mls response and increased the ability of 1-MA, 1-MT, and indo to recover T cell proliferation.