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. Author manuscript; available in PMC: 2010 Dec 14.
Published in final edited form as: Int J Cancer. 2009 Dec 15;125(12):2863–2870. doi: 10.1002/ijc.24748

Fig. 2.

Fig. 2

IκB is degraded in Akt-transformed cells. CEF transfected with vector control, HA-tagged myrAkt (Akt) or HA-tagged Akt-T308A/S473A (Akt-AA) were treated 2 h with either DMSO or the proteasome inhibitor MG132 (2 μM). Whole cell lysates were collected, electrophoresed and immunoblotted with antibodies to IκBα, phospho-S473-Akt, HA or actin. Data presented are representative of three independent experiments.