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Effects of IκBSR on transforming activities of various oncoproteins in CEF
| RCAS vector control |
IκBSR |
|||
|---|---|---|---|---|
| Oncoprotein | FFU/ml | EOT | FFU/ml | EOT |
| v-Src | 9×105 | 1.0 | 3×105 | 0.3 |
| myrP3K | 3×103 | 1.0 | 2×102 | 0.07 |
| myrAkt | 2.8×106 | 1.0 | 1.2×105 | 0.04 |
| v-Jun | 1.8×105 | 1.0 | 6×104 | 0.3 |
FFU, focus-forming units; EOT, efficiency of transformation (FFU/ml on IκBSR- expressing cells divided by FFU/ml on RCAS-transfected cells).
