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. 2009 Oct 26;339:b3794. doi: 10.1136/bmj.b3794

Down’s syndrome diagnoses in England and Wales from 1989/90 to 2007/8 according to year of diagnosis and outcome

Financial year of diagnosis Diagnoses Outcomes of antenatal diagnoses† (%)
All Antenatal Live births
Unknown outcomes Terminations Miscarriages /stillbirths Live births
Reported Estimated*
1989-90 1075 329 752 752 6 93.2 2.5 4.3
1990-1 1106 386 741 742 14 88.4 4.3 7.3
1991-2 1168 445 744 745 11 88.5 4.4 7.1
1992-3 1128 514 625 626 18 92.1 3.2 4.6
1993-4 1218 595 645 646 11 93.2 2.1 4.8
1994-5 1234 622 628 629 24 91.6 3.2 5.2
1995-6 1214 655 582 583 19 91.2 2.8 6.0
1996-7 1352 758 607 608 17 92.7 2.8 4.5
1997-8 1395 733 680 682 32 91.7 2.6 5.7
1998-9 1266 684 610 612 30 91.6 2.0 6.4
1999-00 1348 765 608 610 38 91.9 1.9 6.2
2000-1 1387 822 591 595 70 92.4 1.3 6.3
2001-2 1394 833 588 594 102 91.1 2.7 6.2
2002-3 1481 908 603 609 106 92.4 2.1 5.5
2003-4 1476 877 638 643 79 89.6 2.8 7.6
2004-5 1735 1039 716 725 143 89.8 3.8 6.4
2005-6 1843 1108 746 757 175 91.6 2.8 5.6
2006-7 1825 1108 729 740 176 91.3 3.2 5.5
2007-8 1843 1112 730 743 214 92.8 2.5 4.8
Total 26488 14293 12563 12640 1285 91.5 2.7 5.8

*Estimated live births includes 6% of unknown outcomes.

†Calculated as a proportion of all known outcomes.