Table 1. Biochemical attributes of P4H variants.
| P4H variant | Poly(proline) affinity | Hydroxylase activity | Halogenase activity |
| Wild-type | + | + | − |
| D414A | + | − | − |
| D414G | + | − | − |
| D414H | + | − | nd |
| D414H/H412D | + | − | nd |
| D414H/H438D | + | − | nd |
nd, Not determined.
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