Table 2.
d6-α-Tocopherol | d2-γ-Tocopherol | d2-γ-CEHC | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
corn oil |
sesame oil |
oil | gender | Oil × gender |
corn oil |
sesame oil |
oil | gender | Oil × gender |
corn oil | sesame oil |
oil | gender | Oil × gender |
|
AUC (μmol/L·h) | |||||||||||||||
Women (n=5) |
164 ± 19 |
162 ± 27 |
NS | NS | NS | 20 ± 5 | 21 ± 3 | NS | p<0.07 | NS | 4.8 ± 1.0 |
4.9 ± 0.8 |
p<0.05 | NS | p<0.03 |
Men (n=5) |
194 ± 24 |
193 ± 16 |
29 ± 3 | 34 ± 5 | 5.0 ± 1.0 |
2.6 ± 0.8*,+ |
|||||||||
Cmax (μmol/L) | |||||||||||||||
Women (n=5) |
4.2 ± 0.5 |
4.8 ± 0.4 |
NS | NS | NS | 1.3 ± 0.3 |
1.3 ± 0.2 |
NS | p<0.05 | NS | 0.18 ± 0.05 |
0.29 ± 0.08 |
NS | NS | p<0.01 |
Men (n=5) |
4.3 ± 0.6 |
4.3 ± 0.4 |
1.8 ± 0.3 |
2.0 ± 0.2 |
0.21 ± 0.04 |
0.10 ± 0.03*,+ |
|||||||||
Tmax (h) | |||||||||||||||
Women (n=5) |
16 ± 3 | 16 ± 3 | NS | NS | NS | 10 ± 2 | 16 ± 3 | p<0.03 | NS | NS | 13 ± 3 | 19 ± 5 | p<0.005 | NS | NS |
Men (n=5) |
19 ± 3 | 17 ± 3 | 10 ± 1 | 11 ± 1 | 14 ± 2 | 22 ± 2 | |||||||||
FDR (pools/day) | |||||||||||||||
Women (n=5) |
0.57 ± 0.01 |
0.53 ± 0.02 |
NS | P<0.002 | NS | 2.15 ± 0.14 |
1.94 ± 0.14 |
NS | NS | NS | 1.38 ± 0.09 |
1.48 ± 0.08 |
NS | NS | NS |
Men (n=5) |
0.45 ± 0.01 |
0.42 ± 0.01 |
1.49 ± 0.04 |
1.46 ± 0.05 |
1.2 ± 0.0 |
1.0 ± 0.1 |
Shown are mean ± SEM. No d6-α-CEHC was detected in plasma. Repeated measures MANOVA was performed using JMP Statistical Discovery Software (SAS Institute, Cary, NC) to evaluate effects attributed to oil type and to gender. Where there were significant interactions, post-hoc t-tests were performed;
P<0.05 for paired comparisons of corn vs sesame oil within each gender.
P<0.05 for unpaired comparisons between men and women within each treatment group.