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. 1999 Jan 9;318(7176):81–85. doi: 10.1136/bmj.318.7176.81

Table 6.

Sensitivity and specificity of screening for major defects of heart and great arteries using fetal nuchal translucency thickness. Values are percentages (95% confidence intervals)

Using 95th centile Using 99th centile
Sensitivity 56.0 (42.0 to 70.0) 40.0 (26.0 to 54.0)
Specificity 93.8 (93.6 to 94.1) 99.0 (98.9 to 99.1)
Positive predictive value 1.5 (1.0 to 2.1) 6.3 (3.7 to 9.0)
Negative predictive value  99.9 (99.8 to 100.0)  99.9 (99.8 to 100.0)