Figure 5.

In vivo distribution of ¹²⁵I-VEGF₁₂₁b in tumour-bearing mice. Tumour-bearing mice received an intravenous injection of ¹²⁵I-VEGF₁₂₁b and 3D imaged using NanoSPECT/CT. (A–D) Time course for biodistribution of ¹²⁵I-VEGF₁₂₁b after tail vein injection using transverse sections. (E) Coronal. (F) Para-sagittal through the centre of the tumour. The tumour is circled and arrows indicate different organs. (G) Quantification uptake into different organs and tissues over time. Data expressed as % in tissue relative to the total injected dose, per gram of tissue.