Table 3. Hazard ratios (HR with 95% CI) and numbers of cases for cancers by site and STG quartilesa.
| Cancer site of both sexes ICD-10 codes | Total no. of cases | 1st quartile | 2nd quartile | 3rd quartile | 4th quartile | Total per log-unit increase | P-value for log unit increase |
|---|---|---|---|---|---|---|---|
| Thyroid C73 | (101) | (16) 1.00 | (25) 1.55 (0.82–3.00) | (30) 1.84 (0.97–3.48) | (30) 1.96 (1.00–3.84) | 1.16 (0.76–1.76) | 0.492 |
| Plasmacytoma C90 | (73) | (7) 1.00 | (19) 1.88 (0.74–4.78) | (16) 1.37 (0.52–3.59) | (31) 2.11 (0.82–5.43) | 1.39 (0.84–2.31) | 0.204 |
| NHL C82–C85 | (219) | (42) 1.00 | (61) 0.99 (0.66–1.49) | (54) 0.71 (0.46–1.07) | (62) 0.68 (0.43–1.07) | 0.71 (0.52–0.97) | 0.033 |
| Stomach C16 | (315) | (41) | (80) 1.32 (0.90–1.95) | (83) 1.22 (0.83–1.82) | (111) 1.45 (0.97–2.17) | 1.17 (0.92–1.49) | 0.208 |
| Pancreatic C25 | (162) | (24) 1.00 | (35) 0.99 (0.58–1.69) | (39) 0.86 (0.50–1.47) | (64) 1.19 (0.70–2.05) | 1.25 (0.90–1.75) | 0.188 |
| Colon C18 | (600) | (81) 1.00 | (122) 0.93 (0.70–1.23) | (175) 1.05 (0.80–1.39) | (222) 1.08 (0.81–1.43) | 1.06 (0.88–1.26) | 0.547 |
| Rectal C19/20 | (273) | (32) 1.00 | (69) 1.47 (0.95–2.26) | (69) 1.25 (0.81–1.94 | (103) 1.56 (1.00–2.44) | 1.20 (0.92–1.55) | 0.184 |
| Bladder C67 | (158) | (24) 1.00 | (36) 1.50 (0.48–4.71) | (59) 0.73 (0.22–2.46) | (39) 1.42 (0.45–4.43) | 1.03 (0.98–1.09) | 0.218 |
| Kidney C64 | (216) | (35) 1.00 | (40) 0.81 90.51–1.280 | (51) 0.88 (0.57–1.38) | (90) 1.27 (0.81–1.97) | 1.27 (0.95–1.69) | 0.105 |
| Lung C34 | (650) | (86) 1.00 | (128) (1.12 0.85–1.48) | (179) (1.43 1.09–1.87) | (257) (1.94 1.47–2.54) | 1.50 (1.28–1.75) | <0.0001 |
| Men | |||||||
| Prostate C61 | (1484) | (304) 1.00 | (397) 0.94 (0.80–1.09) | (470) 0.87 (0.75–1.02) | (353) 0.67 (0.56–0.80) | 0.80 (0.72–0.90) | <0.001 |
| Women | |||||||
| Breast C50 ⩽50 years | (510) | (127) 1.00 | (157) 1.25 (0.98–1.59) | (136) 1.23 (0.95–1.59) | (90) 0.95 (0.70–1.28) | 0.92 (0.74–1.15) | 0.455 |
| Breast >50 years | (694) | (75) 1.00 | (135) 0.93 (0.70- 1.24) | 200 1.00 (0.76–1.32) | 284 1.05 (0.79–1.39) | 1.09 (0.91–1.30) | 0.352 |
| Cervical C53 | (70) | (12) 1.00 | (17) 1.48 (0.69–3.19) | (18) 1.52 (0.70–3.34) | (23) 2.00 (0.89- 4.50) | 1.74 (1.03–2.95 | 0.038 |
| Endometrium C54 | (236) | (22) 1.00 | (50) 1.38 (0.83–2.30) | (54) 1.11 (0.66–1.86) | (110) 1.61 (0.97–2.67) | 1.22 (0.90–1.65) | 0.206 |
| Ovarian C56 | (123) | (16) | (29) 1.57 (0.81–3.04) | (39) 1.75 (0.91–3.37) | (39) 1.43 (0.71–2.85) | 1.13 (0.74–1.74) | 0.576 |
| Gynaecological (C53, 54, 56) | (429) | (50) 1.00 | (96) 1.45 (1.01- 2.07) | (111) 1.35 (0.94–1.93) | (172) 1.62 (1.13–2.33) | 1.26 (1.01–1.58) | 0.042 |
a
Adjusted for BMI (kg m−2, continuous), GGT (continuous), serum glucose (continuous), total cholesterol concentration (continuous), smoking status, and occupational status.