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. Author manuscript; available in PMC: 2009 Oct 27.
Published in final edited form as: J Pharmacol Exp Ther. 2008 Aug 28;327(3):910–917. doi: 10.1124/jpet.108.144865

Fig 4. Effects of EtOH on the amplitude and paired-pulse ratio of IPSCs evoked by proximal and distal stimulation in the molecular layer.

Fig 4

A. Sample traces of IPSCs evoked in PNs by pairs of electrical stimuli (50 ms interpulse interval) delivered at the inner (proximal) or outer (distal) thirds of the molecular layer. Note that although 50 mM EtOH minimally affected the proximal IPSCs, it slightly increased the amplitude of the distal IPSC1 and decreased the paired pulse ratio. B. Summary graph illustrating that EtOH did not significantly affect IPSC1 amplitude or the paired-pulse ratio of events evoked by proximal stimulation (n = 8). C. Summary graph illustrating that EtOH significantly affected IPSC1 amplitude (p < 0.006 by one sample t-test vs. a theoretical mean of 100%) and the paired pulse ratio (p < 0.036 by one sample t-test vs. a theoretical mean of 100%) of events evoked by distal stimulation (n = 8).