Skip to main content
. 2009 Aug 18;58(11):2525–2535. doi: 10.2337/db08-1261

FIG. 5.

FIG. 5.

HFD increases macrophage levels in WT skeletal muscle, and diet-induced inflammatory response in muscle is attenuated in MCK-IL10 mice. A: Macrophage-specific CD68 levels in skeletal muscle. B: Immunohistochemistry analysis using anti-CD68 and anti-F4/80 (arrows) in skeletal muscle. C: Skeletal muscle F4/80 levels in immunofluorescence staining. *P < 0.05 vs. WT mice fed a standard diet (A–C). D: Average number of macrophages isolated from muscle samples of standard diet– or HFD-fed WT and MCK-IL10 mice. *P < 0.05 vs. HFD-fed WT mice. E: Representative cytometric data showing the frequency of macrophages (CD11b+F4/80+) in each group. Values are means ± SE for five to seven mice in each experimental group. A two-way ANOVA was used for statistical analysis. (A high-quality color digital representation of this figure is available in the online issue.)