TABLE 4.
Metabolic parameters from hyperinsulinemic-euglycemic clamps in rats
| Low-fat diet | MCFAs | LCFAs | |
|---|---|---|---|
| GIR (mg · kg−1 · min−1) | 38.4 ± 1.6 | 31.4 ± 1.3* | 21.5 ± 1.6*† |
| Rd (mg · kg−1 · min−1) | 36.9 ± 1.3 | 34.3 ± 1.1 | 25.9 ± 1.9*† |
| HGO (mg · kg−1 · min−1) | −1.5 ± 0.63 | 3.0 ± 1.1* | 4.3 ± 0.4*† |
| Rg´ (red quadriceps) | 29.4 ± 2.0 | 26.5 ± 1.8 | 16.9 ± 2.7*† |
| Rg´ (red gastrocnemius) | 29.7 ± 2.8 | 26.8 ± 1.4 | 17.6 ± 0.8*† |
| Rg´ (white gastrocnemius) | 7.1 ± 0.6 | 9.0 ± 0.6* | 5.4 ± 0.4*† |
| Rg´ (epididymal fat) | 1.8 ± 0.2 | 2.2 ± 0.2 | 1.0 ± 0.1*† |
Data are means ± SE for n = 5–7 animals. Plasma levels of glucose and insulin were similar for all groups during the clamp (data not shown).
*P < 0.01 vs. low fat;
†P < 0.01 vs. MCFA. Rg´, insulin-stimulated 3H-2-deoxyglucose uptake in skeletal muscle or adipose tissue during the clamp (μmol · 100 g−1 · min−1).