TABLE 3.
SNP | Position | Location | Risk allele (nonrisk allele) | Genetic model |
||
---|---|---|---|---|---|---|
Additive | Dominant | Recessive | ||||
Shimazaki et al. (ref. 10): Japanese, type 2 diabetes, diabetic nephropathy* | ||||||
rs7804092 | 36,859,757 | 3' flanking region | T(A) | 0.38 | 0.56 | 0.20 |
rs1558688 | 36,881,710 | Intron 19 | C(T) | 0.13 | 0.55 | 0.03 |
rs741301 | 36,884,520 | Intron 18 | T(C) | 0.06 | 0.33 | 0.03 |
rs7799004 | 36,895,489 | Intron 17 | T(C) | 0.02 | 0.06 | 0.05 |
rs11983698 | 36,915,072 | Intron 16 | T(C) | 0.25 | 0.52 | 0.06 |
rs4723596 | 36,917,569 | Intron 16 | T(C) | 0.51 | 0.81 | 0.17 |
Leak et al. (ref. 14): African American, type 2 diabetes, ESRD | ||||||
rs1345365 | 37,167,138 | Intron 13 | G(A) | 0.46 | 0.54 | 0.81 |
rs1981740 | 37,178,829 | Intron 13 | C(A) | 0.97 | 0.98 | 0.89 |
rs10951509 | 37,180,008 | Intron 13 | G(A) | 0.14 | 0.12 | 0.94 |
rs2058730 | 37,201,281 | Intron 13 | T(C) | 0.94 | 0.54 | 0.32 |
rs2717972 | 37,270,120 | Intron 5 | A(G) | 0.50 | 0.54 | 0.79 |
rs9969311 | 37,381,582 | Intron 1 | G(A) | 0.62 | 0.97 | 0.05 |
SNP positions and locations are in reference to NCBI Build 36.1.
*Three SNPs reported by Shimazaki et al. (ref. 10) (rs3807163, rs4723593, and rs1541727) were not genotyped in HapMap and, therefore, were not imputed in the GoKinD collection.