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Effect of high glucose conditions on formation of ROS. Shown are ethidium-labeled wild-type animals cultured for 15 days under standard (A) and high glucose conditions (B), transgenic glyoxalase-1– overexpressing animals cultured for 15 days under standard (C) and high glucose conditions (D). Shown are animals from a representative experiment out of three independent experiments, each including 100 nematodes.
