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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Hypertension. 2009 Aug 24;54(5):1123–1128. doi: 10.1161/HYPERTENSIONAHA.109.138024

Figure 2. Effect of cocaine on KCl-induced constrictions and [Ca2+]i in pressurized coronary arteries.

Figure 2

KCl-induced changes in arterial diameters and [Ca2+]i were measured simultaneously at intraluminal pressure of 20 mmHg in coronary arteries from 3 month old male and female offspring that had been exposed in utero to saline control or cocaine. A, Typical recordings of KCl-induced increase of [Ca2+]i and decrease of the arterial diameter in the same tissue. B, KCl-induced increases of [Ca2+]i (Δ [Ca2+]i, Rf340/380). C, KCl-induced decreases of the arterial diameter (Δ diameter, µm). Data are means ± SEM. * P < 0.05, female versus male. n=5–7 rats.