Optimized p-type epitaxial piezoresistive cantilevers for several choices of instrumentation amplifier. Optimization was performed for operation from 1 Hz to 50 kHz with a minimum thickness of 1 μmW, and maximum bias voltage of 10 V. Three amplifiers were considered: TI INA103, AD622, and AD623. The amplifiers were chosen to represent several price points and noise levels. Although the integrated noise of the AD622 and AD623 are 3 times and 17 times greater than that of the INA103, the minimum detectable force only increases by 10% and 70%, respectively. As the instrumentation amplifier noise increases, the piezoresistor is made shorter and thinner, which increases the sensitivity, while the increased 1∕f noise due to the reduction in N negligibly affects the overall noise while it is less than the amplifier noise.