Table 2.

Pain processing-related areas in the absence of attentional or emotional modulations

Region (BA)	MNI coordinates	t score	Cluster size
Contralateral ACC	8, 14, 34	3.466	368
Ipsilateral ACC	−8, 12, 34	3.568	216
Contralateral insula	32, 16, 8	3.737	13,128
	42, 6, −10	4.773
	42, −4, −2	4.246
Contralateral S2	56, −14, 14	5.138
	62, −18, 22	4.111
Ipsilateral insula	−44, 2, 2	3.958	7112
	−34, 2, 6	3.438
	−34, −2, 10	3.446
	−42, −8, 0	4.806
	−42, −10, 2	4.820
	−42, −14, 8	4.394
	−38, −16, 18	3.648
Ipsilateral S2	−50, −24, 22	3.541	1632
Contralateral medialTH	6, −24, 0	5.532	1376
	2, −18, 0	4.839
Contralateral S1	10, −42, 64	4.102	896
	14, −44, 62	3.916

Thalamic and cortical regions show increased BOLD response during the alternating warm/pain condition for the painful stimuli compared with warm nonpainful baseline. Cluster size refers to the size of the cluster in cubed millimeters with t values superior to 2.5. t scores significant in global search are bolded and underlined. t scores and cluster sizes significant in the directed search are indicated in bold.